Low-Level Drug Release-Rate Testing of Ocular Implants Using USP Apparatus 4 Dissolution and HPLC End Analysis
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چکیده
منابع مشابه
Investigation of the Dissolution Characteristics of Nifedipine Extended-Release Formulations Using USP Apparatus 2 and a Novel Dissolution Apparatus
INTRODUCTION Nifedipine is a calcium-channel blocking agent that is widely used in the treatment of angina pectoris and systemic hypertension (1). The pharmacokinetics and pharmacodynamics of nifedipine have been investigated in numerous studies (2–4). Clinical experiences gained with oral nifedipine formulations with immediate-release (IR) characteristics clearly show that a steep rise in the ...
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Introduction Soft gelatin capsule (SGC) formulations are becoming more popular in recent years (1,2). These formulations can mask odors and unpleasant tastes,and are easy to swallow. They are suitable for encapsulation of lipid solutions,suspensions,or paste-like formulations,making them a useful option when formulating poorly water-soluble drugs. Due to the unique properties of SGC formulation...
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Although not listed on the United States Pharmacopeia (USP), like standard USP 2, small volume USP 2 dissolution apparatus has gained a great deal of attention, especially for cases where small amount of drug product is available for testing in research and design step or evaluations are to be made on a tablet containing trace amounts of the active pharmaceutical ingredient. In this work, first...
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ژورنال
عنوان ژورنال: Dissolution Technologies
سال: 2010
ISSN: 1521-298X
DOI: 10.14227/dt170110p12